2. Stem Cell/Wnt Autophagy
  3. Hedgehog Autophagy
  4. Vismodegib (Standard)

Vismodegib (Standard) is the analytical standard of Vismodegib. This product is intended for research and analytical applications. Vismodegib (GDC-0449) is an orally active hedgehog pathway inhibitor with an IC50 of 3 nM. Vismodegib also inhibits P-gp, ABCG2 with IC50 values of 3.0 μM and 1.4 μM, respectively.

For research use only. We do not sell to patients.

Vismodegib (Standard) Chemical Structure

Vismodegib (Standard) Chemical Structure

CAS No. : 879085-55-9

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Description
Molecular Weight

421.30

Formula

C19H14Cl2N2O3S
CAS No.
SMILES

O=C(C1=CC=C(C=C1Cl)S(=O)(C)=O)NC2=CC=C(C(C3=NC=CC=C3)=C2)Cl
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
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Vismodegib (Standard) Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Vismodegib (Standard)879085-55-9HedgehogAutophagyInhibitorinhibitorinhibit

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