1. Cell Cycle/DNA Damage
  2. DNA/RNA Synthesis
  3. WRN inhibitor 16

WRN inhibitor 16 (Example 83) is an orally available WRN inhibitor. WRN inhibitor 16 did not induce tumor regression in the SW48 xenograft mouse tumor model.

For research use only. We do not sell to patients.

WRN inhibitor 16 Chemical Structure

WRN inhibitor 16 Chemical Structure

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Description

WRN inhibitor 16 (Example 83) is an orally available WRN inhibitor. WRN inhibitor 16 did not induce tumor regression in the SW48 xenograft mouse tumor model.

Molecular Weight

646.65

Formula

C31H30F4N4O5S

SMILES

CC1=NC2=C(N1C)C=CC(S(=O)(N(C3=CC=C(C=C3)[C@H]4CCC[C@H]([C@@H]4C(O)=O)C(NC5=CC=C(C=C5F)C(F)(F)F)=O)C)=O)=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
WRN inhibitor 16
Cat. No.:
HY-169422
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