1. Cell Cycle/DNA Damage
  2. Deubiquitinase
  3. XH161-180

XH161-180 is a potent and orally active ubiquitin carboxyl-terminal hydrolase 2 (USP2) inhibitor. XH161-180 decreases the protein of cyclin D and ACE2. XH161-180 shows antiproliferative activity. XH161-180 has the potential for the research of cancer and virus infection depending on ACE2.

For research use only. We do not sell to patients.

XH161-180 Chemical Structure

XH161-180 Chemical Structure

CAS No. : 3058588-52-3

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Description

XH161-180 is a potent and orally active ubiquitin carboxyl-terminal hydrolase 2 (USP2) inhibitor. XH161-180 decreases the protein of cyclin D and ACE2. XH161-180 shows antiproliferative activity. XH161-180 has the potential for the research of cancer and virus infection depending on ACE2[1].

Molecular Weight

538.45

Formula

C22H21BrFN3O3S2

CAS No.
SMILES

O=C(NC1=NC(C2=CC=C(Br)C=C2)=CS1)C3=CC=C(F)C=C3NS(=O)(C4CCCCC4)=O

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Room temperature in continental US; may vary elsewhere.

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Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
XH161-180
Cat. No.:
HY-168267
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