XMT-1519 conjugate-1 TFA 

XMT-1519 conjugate-1 (compound 31) TFA is a linker for the HER-2 monoclonal antibody XMT-1519, which can be used to synthesize ADC and increase anti-tumor activity^[1].

2471.42

C₁₀₃H₁₅₀F₃N₂₃O₄₄

O=C(C1=C(N=C(O1)C)CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCCOC([C@H](C)NC(CCOCCOCCNC(CC[C@@H](C(NCC(NCC(NCC(NCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCC(N[C@@H](CCC(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)C(NC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)=O)=O)=O)=O)=O)=O)NC(CN6C(C=CC6=O)=O)=O)=O)=O)=O)C=C(C(N)=O)C=C5N=C4NC(C7=C(N=C(O7)C)CC)=O.OC(C(F)(F)F)=O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Jeremy R. Duvall, et al. Antibody drug conjugates comprising sting agonists. WO2021202984 A1.