2. Vitamin D Related/Nuclear Receptor
  3. Androgen Receptor
  4. Zanoterone

Zanoterone is an orally active antagonist of the androgen receptor (AR) with a Ki of 2.2 μM. Zanoterone blocks the binding of androgens such as testosterone and dihydrotestosterone (DHT), inhibiting the androgen signaling pathway, thereby reducing androgen-dependent prostate hyperplasia and prostate cancer growth.

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Zanoterone Chemical Structure

Zanoterone Chemical Structure

CAS No. : 107000-34-0

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Zanoterone Related Antibodies

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Description

Zanoterone is an orally active antagonist of the androgen receptor (AR) with a Ki of 2.2 μM. Zanoterone blocks the binding of androgens such as testosterone and dihydrotestosterone (DHT), inhibiting the androgen signaling pathway, thereby reducing androgen-dependent prostate hyperplasia and prostate cancer growth[1].

Molecular Weight

416.58

Formula

C23H32N2O3S
CAS No.
SMILES

C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])CC4=NN(S(C)(=O)=O)C=C4C2)([H])[C@@]5([H])[C@](CC3)([C@@](O)(CC5)C#C)C
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Zanoterone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zanoterone107000-34-0WIN 49596WIN49596WIN-49596Androgen ReceptorAR AntagonistTestosterone BlockerDihydrotestosterone InhibitorInhibitorinhibitorinhibit

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