2. Immunology/Inflammation
  3. NOD-like Receptor (NLR)
  4. ZM640

ZM640 is a NLRP3 inhibitor. ZM640 enhances IL-1β release mediated by NLRP3 inflammasome activation in THP-1 cells. ZM640 shows low cytotoxicity.

For research use only. We do not sell to patients.

ZM640 Chemical Structure

ZM640 Chemical Structure

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ZM640 Related Antibodies

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Description

ZM640 is a NLRP3 inhibitor. ZM640 enhances IL-1β release mediated by NLRP3 inflammasome activation in THP-1 cells. ZM640 shows low cytotoxicity[1].

Molecular Weight

603.65

Formula

C28H36F3NO8S
SMILES

O=S(NCC[C@H]1[C@H](CC2)[C@@H](O)[C@@]([C@@]3(O)[C@@H](O)[C@]4([H])C(C)(C)CC5)(C1=O)[C@]2([H])[C@]4(CO3)[C@H]5O)(C6=CC=C(C=C6)C(F)(F)F)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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ZM640 Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

ZM640ZM 640ZM-640NOD-like Receptor (NLR)THP-1IL-1βInhibitorinhibitorinhibit

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