2. Membrane Transporter/Ion Channel
  3. P-glycoprotein
  4. Zosuquidar trihydrochloride (Standard)

Zosuquidar trihydrochloride (Standard) 

Cat. No.: HY-50671R Purity: ≥98%
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Zosuquidar (trihydrochloride) (Standard) is the analytical standard of Zosuquidar (trihydrochloride). This product is intended for research and analytical applications. Zosuquidar (LY335979) trihydrochloride is a P-glycoprotein (P-gp) inhibitor (Ki=59 nM). Zosuquidar trihydrochloride shows anti-tumor activities, and can be used in acute myelogenous leukemia (AML) research.

For research use only. We do not sell to patients.

Zosuquidar trihydrochloride (Standard) Chemical Structure

Zosuquidar trihydrochloride (Standard) Chemical Structure

CAS No. : 167465-36-3

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Description

Zosuquidar (trihydrochloride) (Standard) is the analytical standard of Zosuquidar (trihydrochloride). This product is intended for research and analytical applications. Zosuquidar (LY335979) trihydrochloride is a P-glycoprotein (P-gp) inhibitor (Ki=59 nM). Zosuquidar trihydrochloride shows anti-tumor activities, and can be used in acute myelogenous leukemia (AML) research.

Molecular Weight

636.99

Formula

C32H34Cl3F2N3O2
CAS No.
SMILES

FC1([C@H]2[C@@H]1C3=C([C@@H](C4=CC=CC=C42)N5CCN(CC5)C[C@H](COC6=C7C=CC=NC7=CC=C6)O)C=CC=C3)F.Cl.Cl.Cl
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Zosuquidar trihydrochloride (Standard) Related Classifications

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Zosuquidar trihydrochloride (Standard)167465-36-3P-glycoproteinP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243anti-tumor activityacute myelogenous leukemiaAMLK562HL60CCRF-CEMCEM/VLB100P388P388/ADRMCF7MCF7/ADR27802780ADUCLA-P3UCLA-P3.003VLBInhibitorinhibitorinhibit

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