2. PROTAC
  3. PROTAC Linkers
  4. β-Estradiol-6-one 6-(O-carboxymethyloxime)

β-Estradiol-6-one 6-(O-carboxymethyloxime) 

Cat. No.: HY-133407 Purity: 99.67%
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β-Estradiol-6-one 6-(O-carboxymethyloxime) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

For research use only. We do not sell to patients.

β-Estradiol-6-one 6-(O-carboxymethyloxime) Chemical Structure

β-Estradiol-6-one 6-(O-carboxymethyloxime) Chemical Structure

CAS No. : 35048-47-6

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β-Estradiol-6-one 6-(O-carboxymethyloxime) Related Antibodies

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Description

β-Estradiol-6-one 6-(O-carboxymethyloxime) is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC50 & Target

Alkyl-Chain

 

In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

β-Estradiol-6-one 6-(O-carboxymethyloxime) Related Antibodies
Molecular Weight

359.42

Formula

C20H25NO5
CAS No.
Appearance

Solid

Color

White to light brown

SMILES

OC1=CC=C(C/2=C1)[C@@]3([H])CC[C@@]([C@@H](O)CC4)(C)[C@]4([H])[C@]3([H])CC2=N/OCC(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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β-Estradiol-6-one 6-(O-carboxymethyloxime) Related Classifications

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

β-Estradiol-6-one 6-(O-carboxymethyloxime)35048-47-6PROTAC LinkersInhibitorinhibitorinhibit

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β-Estradiol-6-one 6-(O-carboxymethyloxime)
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