1. Metabolic Enzyme/Protease
  2. Liposome
  3. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine 

Cat. No.: HY-142989 Purity: 97.07%
COA Handling Instructions

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that is a constituent of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs) in a molar ratio of 1.5:1.5:1:1 with 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol, and l-α-phosphatidylserine. PERLs can reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and reduce HIV-1 particle secretion from HIV-1 infected PBMCs.

For research use only. We do not sell to patients.

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine Chemical Structure

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine Chemical Structure

CAS No. : 99296-81-8

Size Price Stock Quantity
Solvent
1 mg(11.39 mM * 100 μL in Chloroform) USD 144 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine is a polyunsaturated phospholipid that is a constituent of lipid monolayers and small unilamellar vesicles. 1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine can be used to prepare endoplasmic reticulum-targeted liposomes (PERLs) in a molar ratio of 1.5:1.5:1:1 with 1,2-didocosahexaenoyl-sn-glycero-3-phosphoethanolamine, l-α-phosphatidylinositol, and l-α-phosphatidylserine. PERLs can reduce cholesterol levels in human peripheral blood mononuclear cells (PBMCs) and reduce HIV-1 particle secretion from HIV-1 infected PBMCs[1].

Molecular Weight

878.17

Formula

C52H80NO8P

CAS No.
Appearance

Liquid

Color

Colorless to light yellow

SMILES

CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(O[C@H](COC(CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CC)=O)COP(OCC[N+](C)(C)C)([O-])=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Solution, -20°C, 2 years

Purity & Documentation

Purity: 97.07%

References
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1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
1,2-Didocosahexaenoyl-sn-glycero-3-phosphocholine
Cat. No.:
HY-142989
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