1,2-Propylene-d₆ carbonate

Cat. No.: HY-W032349S Purity: 98.65%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

1,2-Propylene-d₆ carbonate is the deuterium labeled 1,2-Propylene carbonate[1].

For research use only. We do not sell to patients.

1,2-Propylene-d<sub>6</sub> carbonate Chemical Structure

1,2-Propylene-d₆ carbonate Chemical Structure

CAS No. : 202480-74-8

Size	Price	Stock	Quantity
5 mg	USD 55	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 190	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Purity & Documentation
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Description

1,2-Propylene-d₆ carbonate is the deuterium labeled 1,2-Propylene carbonate[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

108.13

Formula

C₄D₆O₃

CAS No.

202480-74-8

Appearance

Liquid

Color

Colorless to light yellow

SMILES

O=C1OC([2H])(C([2H])([2H])[2H])C([2H])([2H])O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 100 mg/mL (924.81 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	9.2481 mL	46.2406 mL	92.4813 mL
5 mM	1.8496 mL	9.2481 mL	18.4963 mL
10 mM	0.9248 mL	4.6241 mL	9.2481 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: 98.65%

Select Batch:

Data Sheet (273 KB) SDS (393 KB)

COA (253 KB) HNMR (533 KB) RP-HPLC (1083 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	9.2481 mL	46.2406 mL	92.4813 mL	231.2032 mL
	5 mM	1.8496 mL	9.2481 mL	18.4963 mL	46.2406 mL
	10 mM	0.9248 mL	4.6241 mL	9.2481 mL	23.1203 mL
	15 mM	0.6165 mL	3.0827 mL	6.1654 mL	15.4135 mL
	20 mM	0.4624 mL	2.3120 mL	4.6241 mL	11.5602 mL
	25 mM	0.3699 mL	1.8496 mL	3.6993 mL	9.2481 mL
	30 mM	0.3083 mL	1.5414 mL	3.0827 mL	7.7068 mL
	40 mM	0.2312 mL	1.1560 mL	2.3120 mL	5.7801 mL
	50 mM	0.1850 mL	0.9248 mL	1.8496 mL	4.6241 mL
	60 mM	0.1541 mL	0.7707 mL	1.5414 mL	3.8534 mL
	80 mM	0.1156 mL	0.5780 mL	1.1560 mL	2.8900 mL
	100 mM	0.0925 mL	0.4624 mL	0.9248 mL	2.3120 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.