2. Immunology/Inflammation
  3. NO Synthase
  4. 1,4-PBIT dihydrobromide

1,4-PBIT dihydrobromide  (Synonyms: 1,4-PB-ITU dihydrobromide)

Cat. No.: HY-135224
Handling Instructions

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1,4-PBIT (1,4-PB-ITU) dihydrobromide (compound 46) is a potent nitric oxide synthases (NOS) inhibitor, with Ki values of 7.6 nM, 360 nM, and 16 nM for the inducible (iNOS), endothelial (eNOS), and neuronal (nNOS) isozymes, respectively.

For research use only. We do not sell to patients.

1,4-PBIT dihydrobromide Chemical Structure

1,4-PBIT dihydrobromide Chemical Structure

CAS No. : 157254-60-9

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Based on 1 publication(s) in Google Scholar

1,4-PBIT dihydrobromide Related Antibodies

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nNOS iNOS eNOS

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Description

1,4-PBIT (1,4-PB-ITU) dihydrobromide (compound 46) is a potent nitric oxide synthases (NOS) inhibitor, with Ki values of 7.6 nM, 360 nM, and 16 nM for the inducible (iNOS), endothelial (eNOS), and neuronal (nNOS) isozymes, respectively[1].

IC50 & Target[1]

iNOS

7.6 nM (Ki)

eNOS

360 nM (Ki)

nNOS

16 nM (Ki)

Molecular Weight

444.25

Formula

C12H20Br2N4S2
CAS No.
SMILES

NC(SCCC1=CC=C(CCSC(N)=N)C=C1)=N.[H]Br.[H]Br
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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1,4-PBIT dihydrobromide Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1,4-PBIT dihydrobromide157254-60-91,4-PB-ITU dihydrobromideNO SynthaseNitric oxide synthasesNOSNOS InhibitoreNOSnNOSiNOSInhibitorinhibitorinhibit

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