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  3. 1,8-Diamino-4,5-dihydroxyanthraquinone

1,8-Diamino-4,5-dihydroxyanthraquinone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

For research use only. We do not sell to patients.

1,8-Diamino-4,5-dihydroxyanthraquinone Chemical Structure

1,8-Diamino-4,5-dihydroxyanthraquinone Chemical Structure

CAS No. : 128-94-9

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Description

1,8-Diamino-4,5-dihydroxyanthraquinone is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.

Cellular Effect
Cell Line Type Value Description References
HEK-293T CC50
> 250 μM
Compound: 2
Cytotoxicity against human HEK293T cells assessed as decrease in cell viability by MTT assay
Cytotoxicity against human HEK293T cells assessed as decrease in cell viability by MTT assay
[PMID: 25856229]
HEK-293T IC50
16 μM
Compound: 24; AL18
Inhibition of Influenza A virus A/WSN/1933(H1N1) PA/PB1 interaction transfected in HEK293T cells assessed as inhibition of viral growth measured after 24 hrs by minireplicon assay
Inhibition of Influenza A virus A/WSN/1933(H1N1) PA/PB1 interaction transfected in HEK293T cells assessed as inhibition of viral growth measured after 24 hrs by minireplicon assay
[PMID: 27046062]
MDCK CC50
> 250 μM
Compound: 24; AL18
Cytotoxicity against MDCK cells measured after 24 to 120 hrs by MTT assay
Cytotoxicity against MDCK cells measured after 24 to 120 hrs by MTT assay
[PMID: 27046062]
MDCK EC50
13 μM
Compound: 24; AL18
Antiviral activity at Influenza A virus infected in MDCK cells by plaque reduction assay
Antiviral activity at Influenza A virus infected in MDCK cells by plaque reduction assay
[PMID: 27046062]
MDCK EC50
14 μM
Compound: 24; AL18
Inhibition of Influenza A virus A/PR/8/34(H1N1) RNA-dependent-RNA polymerase transfected in MDCK cells assessed as reduction in viral growth after 24 hrs by minireplicon assay
Inhibition of Influenza A virus A/PR/8/34(H1N1) RNA-dependent-RNA polymerase transfected in MDCK cells assessed as reduction in viral growth after 24 hrs by minireplicon assay
[PMID: 27046062]
MDCK EC50
14.5 μM
Compound: 2
Antiviral activity against Influenza A virus (A/PR/8/34) (H1N1) infected in MDCK cells assessed as reduction in plaque formation after 48 hrs by plaque reduction assay
Antiviral activity against Influenza A virus (A/PR/8/34) (H1N1) infected in MDCK cells assessed as reduction in plaque formation after 48 hrs by plaque reduction assay
[PMID: 25856229]
MDCK EC50
8.3 μM
Compound: 24; AL18
Inhibition of Influenza B virus B/Lee/40 RNA-dependent-RNA polymerase transfected in MDCK cells assessed as reduction in viral growth after 24 hrs by minireplicon assay
Inhibition of Influenza B virus B/Lee/40 RNA-dependent-RNA polymerase transfected in MDCK cells assessed as reduction in viral growth after 24 hrs by minireplicon assay
[PMID: 27046062]
Molecular Weight

270.24

Formula

C14H10N2O4

CAS No.
SMILES

O=C1C2=C(C(O)=CC=C2N)C(C3=C(O)C=CC(N)=C13)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
1,8-Diamino-4,5-dihydroxyanthraquinone
Cat. No.:
HY-D0299
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