1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 1-Methyluric acid

1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels.

For research use only. We do not sell to patients.

1-Methyluric acid Chemical Structure

1-Methyluric acid Chemical Structure

CAS No. : 708-79-2

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Based on 1 publication(s) in Google Scholar

Other Forms of 1-Methyluric acid:

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Description

1-Methyluric acid acts on the urinary bladder mucosa and increases the blood glucose, insulin, triglyceride, and cholesterol levels.

IC50 & Target

Human Endogenous Metabolite

 

In Vivo

Perfusion of the urinary bladder with 1-Methyl uric acid solution shows an increase in the serum total cholesterol level, true triglyceride level, glucose level and insulin level on comparison with perfusion of the urinary bladder with distilled water[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

182.14

Formula

C6H6N4O3

CAS No.
Appearance

Solid

Color

White to light brown

SMILES

CN(C(O)=N1)C(C2=C1NC(O)=N2)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : < 1 mg/mL (insoluble or slightly soluble)

H2O : < 0.1 mg/mL (insoluble)

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Working solution concentration: mg/mL
Purity & Documentation

Purity: ≥99.0%

References
Animal Administration
[1]

Rats[1]
Adult albino rats of Wistar strain of either sex weighing 200-300 g rats are used for the present study. Thirty albino rats are divided into three groups of ten each. Group I serves as the control group perfused with distilled water. Following cannulation, the bladder is perfused with distilled water. Group II serves as the uric acid perfused group. Group III serves as the 1-Methyl uric acid perfused group. The animals of this group are treated in a similar way as those of control group (Group I) except that the bladder is perfused with the aqueous solution of 1-Methyl uric acid (0.0024 g/100 mL) instead of distilled water[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
1-Methyluric acid
Cat. No.:
HY-W010031
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