1-Aminocyclobutanecarboxylic acid

Name: 1-Aminocyclobutanecarboxylic acid
Brand: MedChemExpress
SKU: HY-30006
Rating: 4.5 (1 reviews)

Cat. No.: HY-30006 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist acting at the glycine site, NR1.

For research use only. We do not sell to patients.

1-Aminocyclobutanecarboxylic acid Chemical Structure

CAS No. : 22264-50-2

Size	Price	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water ready for reconstitution	USD 36	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in Water	USD 36	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	USD 33	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 50	In-stock	Estimated Time of Arrival: December 31
25 mg	USD 100	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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Biological Activity
Purity & Documentation
References
Customer Review

Description

1-Aminocyclobutanecarboxylic acid is a NMDA receptor partial agonist acting at the glycine site, NR1^[1].

IC₅₀ & Target

NMDA Receptor

Molecular Weight

115.13

Formula

C₅H₉NO₂

CAS No.

22264-50-2

Appearance

Solid

Color

Off-white to gray

SMILES

O=C(C1(N)CCC1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Solvent & Solubility

In Vitro:

H₂O : 27.78 mg/mL (241.29 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	8.6858 mL	43.4292 mL	86.8583 mL
5 mM	1.7372 mL	8.6858 mL	17.3717 mL
10 mM	0.8686 mL	4.3429 mL	8.6858 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo:

For the following dissolution methods, please prepare the working solution directly. It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS
Solubility: 33.33 mg/mL (289.50 mM); Clear solution; Need ultrasonic

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (272 KB) SDS (393 KB)

COA (250 KB) HNMR (273 KB)

Handling Instructions (2659 KB)

References

[1]. Atsushi Inanobe, et al. Mechanism of partial agonist action at the NR1 subunit of NMDA receptors. Neuron. 2005 Jul 7;47(1):71-84. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	8.6858 mL	43.4292 mL	86.8583 mL	217.1458 mL
	5 mM	1.7372 mL	8.6858 mL	17.3717 mL	43.4292 mL
	10 mM	0.8686 mL	4.3429 mL	8.6858 mL	21.7146 mL
	15 mM	0.5791 mL	2.8953 mL	5.7906 mL	14.4764 mL
	20 mM	0.4343 mL	2.1715 mL	4.3429 mL	10.8573 mL
	25 mM	0.3474 mL	1.7372 mL	3.4743 mL	8.6858 mL
	30 mM	0.2895 mL	1.4476 mL	2.8953 mL	7.2382 mL
	40 mM	0.2171 mL	1.0857 mL	2.1715 mL	5.4286 mL
	50 mM	0.1737 mL	0.8686 mL	1.7372 mL	4.3429 mL
	60 mM	0.1448 mL	0.7238 mL	1.4476 mL	3.6191 mL
	80 mM	0.1086 mL	0.5429 mL	1.0857 mL	2.7143 mL
	100 mM	0.0869 mL	0.4343 mL	0.8686 mL	2.1715 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.