1-Aminocyclopropane-1-carboxylic acid-d₄

Name: 1-Aminocyclopropane-1-carboxylic acid-d 4
Brand: MedChemExpress
SKU: HY-30004S
Rating: 4.5 (1 reviews)

Cat. No.: HY-30004S Purity: ≥99.0%: FAQs
Data Sheet SDS COA Handling Instructions

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1-Aminocyclopropane-1-carboxylic acid-d₄ is the deuterium labeled 1-Aminocyclopropane-1-carboxylic acid. Aminocyclopropane-1-carboxylic acid is an endogenous metabolite[1].

For research use only. We do not sell to patients.

1-Aminocyclopropane-1-carboxylic acid-d<sub>4</sub> Chemical Structure

1-Aminocyclopropane-1-carboxylic acid-d₄ Chemical Structure

CAS No. : 84392-07-4

Size	Price	Stock	Quantity
1 mg	USD 270	In-stock	Estimated Time of Arrival: December 31
5 mg	USD 540	In-stock	Estimated Time of Arrival: December 31
10 mg	USD 750	In-stock	Estimated Time of Arrival: December 31
50 mg		Get quote
100 mg		Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of 1-Aminocyclopropane-1-carboxylic acid-d₄:

1-Aminocyclopropane-1-carboxylic acid Get quote

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Purity & Documentation
References
Customer Review

Description

1-Aminocyclopropane-1-carboxylic acid-d₄ is the deuterium labeled 1-Aminocyclopropane-1-carboxylic acid. Aminocyclopropane-1-carboxylic acid is an endogenous metabolite[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

105.13

Formula

C₄H₃D₄NO₂

CAS No.

84392-07-4

Unlabeled CAS

22059-21-8

Appearance

Solid

Color

White to off-white

SMILES

[2H]C1([2H])C([2H])([2H])C1(C(O)=O)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (951.20 mM)

DMSO : < 1 mg/mL (insoluble or slightly soluble)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	9.5120 mL	47.5602 mL	95.1203 mL
5 mM	1.9024 mL	9.5120 mL	19.0241 mL
10 mM	0.9512 mL	4.7560 mL	9.5120 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥99.0%

Select Batch:

Data Sheet (274 KB) SDS (393 KB)

COA (253 KB) HNMR (752 KB) RP-HPLC (825 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	9.5120 mL	47.5602 mL	95.1203 mL	237.8008 mL
	5 mM	1.9024 mL	9.5120 mL	19.0241 mL	47.5602 mL
	10 mM	0.9512 mL	4.7560 mL	9.5120 mL	23.7801 mL
	15 mM	0.6341 mL	3.1707 mL	6.3414 mL	15.8534 mL
	20 mM	0.4756 mL	2.3780 mL	4.7560 mL	11.8900 mL
	25 mM	0.3805 mL	1.9024 mL	3.8048 mL	9.5120 mL
	30 mM	0.3171 mL	1.5853 mL	3.1707 mL	7.9267 mL
	40 mM	0.2378 mL	1.1890 mL	2.3780 mL	5.9450 mL
	50 mM	0.1902 mL	0.9512 mL	1.9024 mL	4.7560 mL
	60 mM	0.1585 mL	0.7927 mL	1.5853 mL	3.9633 mL
	80 mM	0.1189 mL	0.5945 mL	1.1890 mL	2.9725 mL
	100 mM	0.0951 mL	0.4756 mL	0.9512 mL	2.3780 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.