1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 1-Methyl-L-histidine-d3

1-Methyl-L-histidine-d3 is the deuterium labeled 1-Methyl-L-histidine. 1-Methyl-L-histidine is an objective indicator of meat ingestion and exogenous 3-methylhistidine (3MH) intake.

For research use only. We do not sell to patients.

1-Methyl-L-histidine-d<sub>3</sub> Chemical Structure

1-Methyl-L-histidine-d3 Chemical Structure

CAS No. : 91037-48-8

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1 mg USD 30 In-stock
5 mg USD 80 In-stock
10 mg USD 130 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 1-Methyl-L-histidine-d3:

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  • Biological Activity

  • Purity & Documentation

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Description

1-Methyl-L-histidine-d3 is the deuterium labeled 1-Methyl-L-histidine. 1-Methyl-L-histidine is an objective indicator of meat ingestion and exogenous 3-methylhistidine (3MH) intake.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

172.20

Formula

C7H8D3N3O2

CAS No.
Unlabeled CAS

332-80-9

Appearance

Solid

Color

Off-white to light yellow

SMILES

OC([C@@H](N)CC1=CN(C([2H])([2H])[2H])C=N1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 125 mg/mL (725.90 mM; Need ultrasonic)

H2O : 125 mg/mL (725.90 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.8072 mL 29.0360 mL 58.0720 mL
5 mM 1.1614 mL 5.8072 mL 11.6144 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.40%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 5.8072 mL 29.0360 mL 58.0720 mL 145.1800 mL
5 mM 1.1614 mL 5.8072 mL 11.6144 mL 29.0360 mL
10 mM 0.5807 mL 2.9036 mL 5.8072 mL 14.5180 mL
15 mM 0.3871 mL 1.9357 mL 3.8715 mL 9.6787 mL
20 mM 0.2904 mL 1.4518 mL 2.9036 mL 7.2590 mL
25 mM 0.2323 mL 1.1614 mL 2.3229 mL 5.8072 mL
30 mM 0.1936 mL 0.9679 mL 1.9357 mL 4.8393 mL
40 mM 0.1452 mL 0.7259 mL 1.4518 mL 3.6295 mL
50 mM 0.1161 mL 0.5807 mL 1.1614 mL 2.9036 mL
60 mM 0.0968 mL 0.4839 mL 0.9679 mL 2.4197 mL
80 mM 0.0726 mL 0.3630 mL 0.7259 mL 1.8148 mL
100 mM 0.0581 mL 0.2904 mL 0.5807 mL 1.4518 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Product Name:
1-Methyl-L-histidine-d3
Cat. No.:
HY-W017006S
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