1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 1-Methylhistamine-d3 dihydrochloride

1-Methylhistamine-d3 dihydrochloride 

Cat. No.: HY-W053787S Purity: 99.91%
SDS COA Handling Instructions Technical Support

1-Methylhistamine-d3 (dihydrochloride) is the deuterium labeled 1-Methylhistamine (dihydrochloride)[1]. 1-Methylhistamine dihydrochloride is a histamine metabolite[2].

For research use only. We do not sell to patients.

1-Methylhistamine-d<sub>3</sub> dihydrochloride Chemical Structure

1-Methylhistamine-d3 dihydrochloride Chemical Structure

CAS No. : 344299-49-6

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Other Forms of 1-Methylhistamine-d3 dihydrochloride:

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Description

1-Methylhistamine-d3 (dihydrochloride) is the deuterium labeled 1-Methylhistamine (dihydrochloride)[1]. 1-Methylhistamine dihydrochloride is a histamine metabolite[2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

201.11

Formula

C6H10D3Cl2N3

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

NCCC1=CN(C([2H])([2H])[2H])C=N1.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

H2O : 62.5 mg/mL (310.78 mM; Need ultrasonic and warming)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9724 mL 24.8620 mL 49.7240 mL
5 mM 0.9945 mL 4.9724 mL 9.9448 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.9724 mL 24.8620 mL 49.7240 mL 124.3101 mL
5 mM 0.9945 mL 4.9724 mL 9.9448 mL 24.8620 mL
10 mM 0.4972 mL 2.4862 mL 4.9724 mL 12.4310 mL
15 mM 0.3315 mL 1.6575 mL 3.3149 mL 8.2873 mL
20 mM 0.2486 mL 1.2431 mL 2.4862 mL 6.2155 mL
25 mM 0.1989 mL 0.9945 mL 1.9890 mL 4.9724 mL
30 mM 0.1657 mL 0.8287 mL 1.6575 mL 4.1437 mL
40 mM 0.1243 mL 0.6216 mL 1.2431 mL 3.1078 mL
50 mM 0.0994 mL 0.4972 mL 0.9945 mL 2.4862 mL
60 mM 0.0829 mL 0.4144 mL 0.8287 mL 2.0718 mL
80 mM 0.0622 mL 0.3108 mL 0.6216 mL 1.5539 mL
100 mM 0.0497 mL 0.2486 mL 0.4972 mL 1.2431 mL
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Product Name:
1-Methylhistamine-d3 dihydrochloride
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HY-W053787S
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