2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 11-Dehydrocorticosterone

11-Dehydrocorticosterone is a endogenous corticosteroid. 11-Dehydrocorticosterone can be a source of transcriptionally active glucocorticoid in cardiac myocytes and fibroblasts. 11-Dehydrocorticosterone can increase SGK mRNA expression in cardiac fibroblast.

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11-Dehydrocorticosterone Chemical Structure

11-Dehydrocorticosterone Chemical Structure

CAS No. : 72-23-1

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Based on 1 publication(s) in Google Scholar

11-Dehydrocorticosterone Related Antibodies

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1 Publications Citing Use of MCE 11-Dehydrocorticosterone

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Description

11-Dehydrocorticosterone is a endogenous corticosteroid. 11-Dehydrocorticosterone can be a source of transcriptionally active glucocorticoid in cardiac myocytes and fibroblasts. 11-Dehydrocorticosterone can increase SGK mRNA expression in cardiac fibroblast[1].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

344.44

Formula

C21H28O4
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]1(C2)[C@@H](C(CO)=O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])C2=O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 30 mg/mL (87.10 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9033 mL 14.5163 mL 29.0326 mL
5 mM 0.5807 mL 2.9033 mL 5.8065 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9033 mL 14.5163 mL 29.0326 mL 72.5816 mL
5 mM 0.5807 mL 2.9033 mL 5.8065 mL 14.5163 mL
10 mM 0.2903 mL 1.4516 mL 2.9033 mL 7.2582 mL
15 mM 0.1936 mL 0.9678 mL 1.9355 mL 4.8388 mL
20 mM 0.1452 mL 0.7258 mL 1.4516 mL 3.6291 mL
25 mM 0.1161 mL 0.5807 mL 1.1613 mL 2.9033 mL
30 mM 0.0968 mL 0.4839 mL 0.9678 mL 2.4194 mL
40 mM 0.0726 mL 0.3629 mL 0.7258 mL 1.8145 mL
50 mM 0.0581 mL 0.2903 mL 0.5807 mL 1.4516 mL
60 mM 0.0484 mL 0.2419 mL 0.4839 mL 1.2097 mL
80 mM 0.0363 mL 0.1815 mL 0.3629 mL 0.9073 mL
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11-Dehydrocorticosterone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11-Dehydrocorticosterone72-23-1Endogenous MetaboliteGlucocorticoidcorticosteroidcardiac fibroblastcardiac myocytesInhibitorinhibitorinhibit

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