11-deoxy Prostaglandin F1α (Synonyms: 11-deoxy PGF1α)

Cat. No.: HY-131696: FAQs
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11-deoxy Prostaglandin F1α (11-deoxy PGF1α) is an analog of prostaglandin F1α, exhibits side effects on intestines and causes the uterine contraction. 11-deoxy Prostaglandin F1α exhibits activity as vasopressor and bronchoconstrictor.

For research use only. We do not sell to patients.

11-deoxy Prostaglandin F1α Chemical Structure

CAS No. : 37785-98-1

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Description

In Vivo

11-deoxy PGF1α (0-10 mg/kg, i.v., single dose) stimulates the uterine contraction in pregnant SD rats, while reveals slightly efficacy on hamster fertility^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:	pregnant Sprague-Dawley rats^[1]
Dosage:	0-10 mg/kg
Administration:	i.v., single dose
Result:	Stimulated uterine contraction 3 times active as PGF1α.

Molecular Weight

340.50

Formula

C₂₀H₃₆O₄

CAS No.

37785-98-1

SMILES

OC(CCCCCC[C@@H]1[C@H](CC[C@@H]1O)/C=C/[C@@H](O)CCCCC)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Broughton BJ, et al., Uterine stimulant action of some omega-chain modified (+)-11-deoxyprostaglandins. Prostaglandins. 1981 Jul;22(1):53-64. [Content Brief]

[2]. Hall DW, et al., Structure-activity relationships in a series of 11-deoxy prostaglandins. Prostaglandins. 1976 Mar;11(3):573-87. [Content Brief]

11-deoxy Prostaglandin F1α Related Classifications

Cardiovascular Disease Others

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Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11-deoxy Prostaglandin F1α37785-98-111-deoxy PGF1αOthersguinea pigsSprague-Dawley ratsvasopressorbronchoconstrictorInhibitorinhibitorinhibit

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