2. Metabolic Enzyme/Protease
  3. 11β-HSD
  4. 11β-HSD1-IN-15

11β-HSD1-IN-15 is an inhibitor of 11β-hydroxysteroid dehydrogenase type I (11β-HSD1). 11β-HSD1-IN-15 blocks the conversion of corticosterone to cortisol by binding to the active site of the 11β-HSD1 enzyme. 11β-HSD1-IN-15 can be used to investigate the role of 11β-HSD1 enzymes IN the development of metabolic syndrome, obesity, cognitive decline and type 2 diabetes.

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11β-HSD1-IN-15 Chemical Structure

11β-HSD1-IN-15 Chemical Structure

CAS No. : 946398-78-3

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11β-HSD1-IN-15 Related Antibodies

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Description

11β-HSD1-IN-15 is an inhibitor of 11β-hydroxysteroid dehydrogenase type I (11β-HSD1). 11β-HSD1-IN-15 blocks the conversion of corticosterone to cortisol by binding to the active site of the 11β-HSD1 enzyme. 11β-HSD1-IN-15 can be used to investigate the role of 11β-HSD1 enzymes IN the development of metabolic syndrome, obesity, cognitive decline and type 2 diabetes[1].

Molecular Weight

479.88

Formula

C19H18ClF4N3O3S
CAS No.
SMILES

FC(F)(C1=C(N2C[C@H](N(CC2)S(=O)(C3=C(C=C(C=C3)C(N)=O)Cl)=O)C)C=CC(F)=C1)F
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Room temperature in continental US; may vary elsewhere.
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Purity & Documentation
References
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11β-HSD1-IN-15 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

11β-HSD1-IN-15946398-78-311β-HSD11beta-HSD11β-hydroxysteroid dehydrogenases11 beta-hydroxysteroid dehydrogenasecortisolmetabolic diseasecognitive declinediabetesneurological diseaseInhibitorinhibitorinhibit

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