2. Natural Products
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  4. Myricaceae
  5. Morella adenophora (Hance) J. Herb.
  6. 12-Hydroxymyricanone

12-Hydroxymyricanone is a nature product that could be isolated from the roots of Myrica nana. 12-Hydroxymyricanone inhibits the release of nitric oxide with an IC50 value of 30.19 μM.

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12-Hydroxymyricanone Chemical Structure

12-Hydroxymyricanone Chemical Structure

CAS No. : 191999-68-5

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12-Hydroxymyricanone Related Antibodies

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Description

12-Hydroxymyricanone is a nature product that could be isolated from the roots of Myrica nana. 12-Hydroxymyricanone inhibits the release of nitric oxide with an IC50 value of 30.19 μM[1].

Cellular Effect
Cell Line Type Value Description References
Macrophage IC50
30.19 μM
Compound: 8
Inhibition of LPS-stimulated nitric oxide production in BALB/c mouse macrophages after 20 hrs by Griess assay relative to control
Inhibition of LPS-stimulated nitric oxide production in BALB/c mouse macrophages after 20 hrs by Griess assay relative to control
[PMID: 18723353]
In Vitro

12-Hydroxymyricanone (compound 8; 0-100 μM) inhibits nitric oxide release in Lipopolysaccharides (HY-D1056)-activated peritoneal macrophages[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

12-Hydroxymyricanone Related Antibodies
Molecular Weight

372.41

Formula

C21H24O6
CAS No.
SMILES

COC1=C2C3=C(O)C=CC(CC(C(CCCCC(C(O)=C1OC)=C2)=O)O)=C3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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12-Hydroxymyricanone Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

12-Hydroxymyricanone191999-68-5Othersnature productrootsMyrica nananitric oxideInhibitorinhibitorinhibit

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12-Hydroxymyricanone
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HY-N10857
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