15(R)-15-Methyl Prostaglandin F2α (Synonyms: 15(R)-Carboprost; 15(R)-15-methyl PGF2α)

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15(R)-15-Methyl Prostaglandin F2α (15(R)-Carboprost; 15(R)-15-methyl PGF2α) is a metabolically stable analog of PGF2α. 15(R)-15-Methyl Prostaglandin F2α is an inactive, prodrug PGF agonist designed for activation by gastric acid after oral administration. Acid-catalyzed epimerization of 15(R)-15-Methyl Prostaglandin F2α converts it into the active 15(S)-isomer. The 15(S)-isomer induces luteolysis when injected in rhesus monkeys at a dose of about 12 mg/animal, while the 15(R)-isomer does not.

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15(R)-15-Methyl Prostaglandin F2α Chemical Structure

CAS No. : 35864-81-4

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10 mg		Get quote	Estimated Time of Arrival: December 31

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Description	15(R)-15-Methyl Prostaglandin F2α (15(R)-Carboprost; 15(R)-15-methyl PGF2α) is a metabolically stable analog of PGF2α. 15(R)-15-Methyl Prostaglandin F2α is an inactive, prodrug PGF agonist designed for activation by gastric acid after oral administration. Acid-catalyzed epimerization of 15(R)-15-Methyl Prostaglandin F2α converts it into the active 15(S)-isomer. The 15(S)-isomer induces luteolysis when injected in rhesus monkeys at a dose of about 12 mg/animal, while the 15(R)-isomer does not.
Molecular Weight	368.51
Formula	C₂₁H₃₆O₅
CAS No.	35864-81-4
SMILES	CCCCC[C@@](C)(O)/C=C/[C@@H]1[C@H]([C@@H](O)C[C@H]1O)C/C=C\CCCC(O)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (271 KB) Handling Instructions (2659 KB)
References	[1]. Hamberg, et al. On the pH-dependent degradation of 15(S)-15 methyl-prostaglandin F2α (Carboprost). Eur. J. Pharm. Sci. 3(1), 27-38 (1995).

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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15(R)-15-Methyl Prostaglandin F2α35864-81-415(R)-Carboprost 15(R)-15-methyl PGF2αOthersInhibitorinhibitorinhibit

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15(R)-15-Methyl Prostaglandin F2α (Synonyms: 15(R)-Carboprost; 15(R)-15-methyl PGF2α)

15(R)-15-Methyl Prostaglandin F2α Related Antibodies

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