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  4. 16α,17α-Epoxyprogesterone

16α,17α-Epoxyprogesterone is an important steroid, serving as an intermediate for many hormonal drugs such as Hydrocortisone (HY-N0583) and Megestrol (HY-B1834). 16α,17α-Epoxyprogesterone can further biotransform into another significant intermediate, 11α-hydroxy-16α,17α-epoxyprogesterone, to manufacture additional compounds.

For research use only. We do not sell to patients.

16α,17α-Epoxyprogesterone Chemical Structure

16α,17α-Epoxyprogesterone Chemical Structure

CAS No. : 1097-51-4

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16α,17α-Epoxyprogesterone Related Antibodies

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Description

16α,17α-Epoxyprogesterone is an important steroid, serving as an intermediate for many hormonal drugs such as Hydrocortisone (HY-N0583) and Megestrol (HY-B1834). 16α,17α-Epoxyprogesterone can further biotransform into another significant intermediate, 11α-hydroxy-16α,17α-epoxyprogesterone, to manufacture additional compounds[1].

Molecular Weight

328.45

Formula

C21H28O3
CAS No.
Appearance

Solid

SMILES

CC([C@@]12[C@@](O2)([H])C[C@@]3([H])[C@]4([H])CCC5=CC(CC[C@]5(C)[C@@]4([H])CC[C@]13C)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

Methanol : 10 mg/mL (30.45 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.0446 mL 15.2230 mL 30.4460 mL
5 mM 0.6089 mL 3.0446 mL 6.0892 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

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Volume (start)

V1

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Concentration (final)

C2

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V2

In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Methanol 1 mM 3.0446 mL 15.2230 mL 30.4460 mL 76.1151 mL
5 mM 0.6089 mL 3.0446 mL 6.0892 mL 15.2230 mL
10 mM 0.3045 mL 1.5223 mL 3.0446 mL 7.6115 mL
15 mM 0.2030 mL 1.0149 mL 2.0297 mL 5.0743 mL
20 mM 0.1522 mL 0.7612 mL 1.5223 mL 3.8058 mL
25 mM 0.1218 mL 0.6089 mL 1.2178 mL 3.0446 mL
30 mM 0.1015 mL 0.5074 mL 1.0149 mL 2.5372 mL
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16α,17α-Epoxyprogesterone Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

16α,17α-Epoxyprogesterone1097-51-4Othershormoneschemical synthesisintermediates11α-hydroxy-16α,17α-epoxyprogesteronebiotransformationInhibitorinhibitorinhibit

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