1a,1b-Dihomo prostaglandin E2 (Synonyms: 1a,1b-Dihomo PGE2)

Cat. No.: HY-131626: FAQs
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1a,1b-Dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid. 1a,1b-Dihomo PGE2 has also been identified in conditioned media of RAW 264.7 macrophages stimulated with endotoxin and arachidonic acid. This product is thought to be produced by elongation of AA to adrenic acid, which is then metabolized sequentially by COX and PGE synthase.

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1a,1b-Dihomo prostaglandin E2 Chemical Structure

CAS No. : 26198-80-1

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Description	1a,1b-Dihomo Prostaglandin E2 (PGE2) is a rare polyunsaturated fatty acid first identified in extracts of sheep vesicular gland microsomes, known to contain COX, incubated with adrenic acid. 1a,1b-Dihomo PGE2 has also been identified in conditioned media of RAW 264.7 macrophages stimulated with endotoxin and arachidonic acid. This product is thought to be produced by elongation of AA to adrenic acid, which is then metabolized sequentially by COX and PGE synthase.
Molecular Weight	380.52
Formula	C₂₂H₃₆O₅
CAS No.	26198-80-1
SMILES	O=C(O)CCCCC/C=C\C[C@@H]1[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)CC1=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (268 KB) Handling Instructions (2659 KB)
References	[1]. Harkewicz, et al. Arachidonate-derived dihomoprostaglandin production observed in endotoxin-stimulated macrophage-like cells. J. Biol. Chem. 282(5), 2899-2910 (2007).

1a,1b-Dihomo prostaglandin E2 Related Classifications

Metabolic Disease

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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1a,1b-Dihomo prostaglandin E226198-80-11a,1b-Dihomo PGE2OthersInhibitorinhibitorinhibit

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1a,1b-Dihomo prostaglandin E2 (Synonyms: 1a,1b-Dihomo PGE2)

1a,1b-Dihomo prostaglandin E2 Related Antibodies

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Biological Activity

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