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  4. 2-Amino benzamidoxime

2-Amino benzamidoxime (ABAO compound 6) can react quickly with aldehydes to form stable 1, 2-dihydroquinazoline 3-oxides in aqueous solutions. The 2-Amino benzamidoxime reaction process consists of the formation of a Schiff base as a rate-determining step, followed by rapid intramolecular cyclization. The reaction rate is dependent on pH, indicating that protonated benzamidoxime is involved in the formation of Schiff bases as an internal generalized acid. Substituents on the aromatic ring can increase the alkalinity of the aromatic amine, thus speeding up the reaction. The reactive properties of 2-Amino benzamidoxime make it a potential platform for the development of new bioconjugated strategies, fluorescent probes, and post-translational diversification of genetic coding libraries.

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2-Amino benzamidoxime Chemical Structure

2-Amino benzamidoxime Chemical Structure

CAS No. : 16348-49-5

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2-Amino benzamidoxime Related Antibodies

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Description

2-Amino benzamidoxime (ABAO compound 6) can react quickly with aldehydes to form stable 1, 2-dihydroquinazoline 3-oxides in aqueous solutions. The 2-Amino benzamidoxime reaction process consists of the formation of a Schiff base as a rate-determining step, followed by rapid intramolecular cyclization. The reaction rate is dependent on pH, indicating that protonated benzamidoxime is involved in the formation of Schiff bases as an internal generalized acid. Substituents on the aromatic ring can increase the alkalinity of the aromatic amine, thus speeding up the reaction. The reactive properties of 2-Amino benzamidoxime make it a potential platform for the development of new bioconjugated strategies, fluorescent probes, and post-translational diversification of genetic coding libraries[1].

Molecular Weight

151.17

Formula

C7H9N3O
CAS No.
SMILES

N=C(NO)C1=CC=CC=C1N
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2-Amino benzamidoxime Related Classifications

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Keywords:

2-Amino benzamidoxime16348-49-5ABAOBiochemical Assay ReagentsSchiff baseFluorescent probeprotein bioconjugationBioorthogonal chemistryInhibitorinhibitorinhibit

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