2'-Deoxyguanosine 5'-monophosphate-¹³C₁₀,¹⁵N₅ disodium  (Synonyms: dGMP-¹³C₁₀,¹⁵N₅)

2'-Deoxyguanosine 5'-monophosphate-¹³C₁₀,¹⁵N₅ (disodium) is the ¹³C and ¹⁵N labeled 2'-Deoxyguanosine 5'-monophosphate disodium[1]. 2'-Deoxyguanosine 5'-monophosphate disodium (5′-dGMP disodium) is a mononucleotide having guanine as the nucleobase. 2'-Deoxyguanosine 5'-monophosphate disodium is a nucleic acid guanosine triphosphate (GTP) derivative[2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

406.08

¹³C₁₀H₁₂¹⁵N₅Na₂O₇P

Solid

White to off-white

O=[13C]1[13C]2=[13C]([15N]([13CH]=[15N]2)[13C@@]3([H])[13C]([13C@]([13C@](O3)([13CH2]OP(O[Na])(O[Na])=O)[H])([H])O)([H])[H])[15N]=[13C]([15NH2])[15NH]1

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. M Paula Denofrio, et al. The photosensitizing activity of lumazine using 2'-deoxyguanosine 5'-monophosphate and HeLa cells as targets. Photochem Photobiol Sci. 2009 Nov;8(11):1539-49.  [Content Brief]