2-Ethylhexyl diphenyl phosphate (Synonyms: EHDPP; Octicizer)

Cat. No.: HY-W009066: FAQs
Data Sheet Handling Instructions Technical Support

2-Ethylhexyl diphenyl phosphate is an organophosphate flame retardants (OPFRs) and a PPARG agonist (EC₂₀: 2.04 µM). 2-Ethylhexyl diphenyl phosphate also inhibits ERRγ transcriptional activity (IC₅₀: 1.3 µM). 2-Ethylhexyl diphenyl phosphate upregulates 3β-HSD1, human chorionic gonadotropin (hCG) and progesterone secretion. 2-Ethylhexyl diphenyl phosphate can be used in studies of female reproduction and fetal development.

For research use only. We do not sell to patients.

2-Ethylhexyl diphenyl phosphate Chemical Structure

CAS No. : 1241-94-7

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Estrogen receptor ERα ERβ ERRα ERRβ ERRγ

Biological Activity
Purity & Documentation
References
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Description

IC₅₀ & Target^[1]^[2]

ERRγ

1.3 μM (IC₅₀)

Molecular Weight

362.41

Formula

C₂₀H₂₇O₄P

CAS No.

1241-94-7

SMILES

O=P(OC1=CC=CC=C1)(OCC(CC)CCCC)OC2=CC=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Hu W, et al. Activation of Peroxisome Proliferator-Activated Receptor Gamma and Disruption of Progesterone Synthesis of 2-Ethylhexyl Diphenyl Phosphate in Human Placental Choriocarcinoma Cells: Comparison with Triphenyl Phosphate. Environ Sci Technol. 2017 Apr 4;51(7):4061-4068. [Content Brief]

[2]. Cao L Y, et al. Organophosphate esters bind to and inhibit estrogen-related receptor γ in cells. Environmental Science & Technology Letters, 2018, 5(2): 68-73.

2-Ethylhexyl diphenyl phosphate Related Classifications

Endocrinology

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
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The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-Ethylhexyl diphenyl1241-94-7EHDPP OcticizerPPARProgesterone ReceptorEstrogen Receptor/ERRPeroxisome proliferator-activated receptorsNR3C3Placental choriocarcinomaOPFRFemale reproductionFetal developmentChorionic gonadotropin. JEG-3 cells293T cells.Inhibitorinhibitorinhibit

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