2. Anti-infection
  3. Bacterial
  4. 2'-​Hydroxy-​2-​methoxychalcone

2'-Hydroxy-2-methoxychalcone (compound 3b) is a synthetic chalcone, with antimicrobial activity.

For research use only. We do not sell to patients.

2'-​Hydroxy-​2-​methoxychalcone Chemical Structure

2'-​Hydroxy-​2-​methoxychalcone Chemical Structure

CAS No. : 42220-77-9

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2'-​Hydroxy-​2-​methoxychalcone Related Antibodies

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Description

2'-Hydroxy-2-methoxychalcone (compound 3b) is a synthetic chalcone, with antimicrobial activity[1].

Cellular Effect
Cell Line Type Value Description References
A2780cisR GI50
11.69 μM
Compound: 1
Growth inhibition of cisplatin-resistant human A2780cis cells after 7 days by crystal violet staining based clonogenic assay
Growth inhibition of cisplatin-resistant human A2780cis cells after 7 days by crystal violet staining based clonogenic assay
[PMID: 24565968]
CHO IC50
25.5 μM
Compound: 8a
Cytotoxicity against CHO cells assessed as decrease in cell proliferation after 48 hrs by MTS assay
Cytotoxicity against CHO cells assessed as decrease in cell proliferation after 48 hrs by MTS assay
[PMID: 27161874]
CHO IC50
25.5 μM
Compound: 8a
Cytotoxicity against CHO cells after 48 hrs by MTS assay
Cytotoxicity against CHO cells after 48 hrs by MTS assay
[PMID: 23768434]
HEK-293T EC50
1.4 μM
Compound: 8a
Inverse agonist activity at human cytomegalovirus US28 receptor transfected in HEK293T cells assessed as activation of MAPK signaling pathway after 20 to 24 hrs by luciferase-based Elk1 reporter gene assay
Inverse agonist activity at human cytomegalovirus US28 receptor transfected in HEK293T cells assessed as activation of MAPK signaling pathway after 20 to 24 hrs by luciferase-based Elk1 reporter gene assay
[PMID: 23768434]
Molecular Weight

254.28

Formula

C16H14O3
CAS No.
SMILES

O=C(C1=CC=CC=C1O)/C=C/C2=CC=CC=C2OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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2'-​Hydroxy-​2-​methoxychalcone Related Classifications

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2'-​Hydroxy-​2-​methoxychalcone42220-77-9BacterialInhibitorinhibitorinhibit

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2'-​Hydroxy-​2-​methoxychalcone
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HY-128452
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