1. GPCR/G Protein Neuronal Signaling
  2. 5-HT Receptor
  3. 2-Methyl-5-HT hydrochloride

2-Methyl-5-HT hydrochloride  (Synonyms: 2-Methyl-5-hydroxytryptamine hydrochloride; 2-Methylserotonin hydrochloride; 2-Me-HT hydrochloride)

Cat. No.: HY-19358A
Handling Instructions

2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT hydrochloride is shown to display anti-depressive-like effects.

For research use only. We do not sell to patients.

2-Methyl-5-HT hydrochloride Chemical Structure

2-Methyl-5-HT hydrochloride Chemical Structure

CAS No. : 845861-49-6

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Description

2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) is a potent and selective 5-HT3 receptor agonist. 2-Methyl-5-HT hydrochloride is shown to display anti-depressive-like effects[1].

IC50 & Target[1]

5-HT3 Receptor

 

In Vivo

2-Methyl-5-HT hydrochloride (2-Methyl-5-hydroxytryptamine hydrochloride) (i.p.; 3 mg/kg; 45 minutes) significantly decreases time of immobility as compared to controls thus showing anti-depressive-like effects[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male Sprague-Dawley rats[1]
Dosage: 3 mg/kg
Administration: I.p.; 45 minutes
Result: Significantly decreased time of immobility thus showing anti-depressive-like effects.
Molecular Weight

226.70

Formula

C11H15ClN2O

CAS No.
SMILES

OC1=CC2=C(NC(C)=C2CCN)C=C1.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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2-Methyl-5-HT hydrochloride Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
2-Methyl-5-HT hydrochloride
Cat. No.:
HY-19358A
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