2-Nonyl-3-hydroxy-4-quinolone

Cat. No.: HY-124352 Purity: ≥98.0%: FAQs
Data Sheet SDS COA Handling Instructions Technical Support

2-nonyl-3-hydroxy-4-Quinolone (C9-PQS) is a quinolone compound produced by P. aeruginosa and other related bacterias. 2-nonyl-3-hydroxy-4-Quinolone is a quorum sensing (QS) signal molecule that controls the expression of many virulence genes as a function of cell population density.

For research use only. We do not sell to patients.

2-Nonyl-3-hydroxy-4-quinolone Chemical Structure

CAS No. : 1259944-03-0

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	Get quote
10 mg	Get quote

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Based on 1 publication(s) in Google Scholar

Other Forms of 2-Nonyl-3-hydroxy-4-quinolone:

2-Nonyl-3-hydroxy-4-quinolone-d₄ Get quote

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

287.40

Formula

C₁₈H₂₅NO₂

CAS No.

1259944-03-0

Appearance

Solid

Color

White to off-white

SMILES

O=C1C(O)=C(NC2=C1C=CC=C2)CCCCCCCCC

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 25 mg/mL (86.99 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.4795 mL	17.3974 mL	34.7947 mL
5 mM	0.6959 mL	3.4795 mL	6.9589 mL
10 mM	0.3479 mL	1.7397 mL	3.4795 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Concentration _(final)

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: ≥98.0%

Select Batch:

Data Sheet (265 KB) SDS (251 KB)

COA (242 KB)

Handling Instructions (2659 KB)

References

[1]. Heeb S, et al. Quinolones: from antibiotics to autoinducers. FEMS Microbiol Rev. 2011 Mar;35(2):247-74. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.4795 mL	17.3974 mL	34.7947 mL	86.9868 mL
	5 mM	0.6959 mL	3.4795 mL	6.9589 mL	17.3974 mL
	10 mM	0.3479 mL	1.7397 mL	3.4795 mL	8.6987 mL
	15 mM	0.2320 mL	1.1598 mL	2.3196 mL	5.7991 mL
	20 mM	0.1740 mL	0.8699 mL	1.7397 mL	4.3493 mL
	25 mM	0.1392 mL	0.6959 mL	1.3918 mL	3.4795 mL
	30 mM	0.1160 mL	0.5799 mL	1.1598 mL	2.8996 mL
	40 mM	0.0870 mL	0.4349 mL	0.8699 mL	2.1747 mL
	50 mM	0.0696 mL	0.3479 mL	0.6959 mL	1.7397 mL
	60 mM	0.0580 mL	0.2900 mL	0.5799 mL	1.4498 mL
	80 mM	0.0435 mL	0.2175 mL	0.4349 mL	1.0873 mL