2. Immunology/Inflammation Vitamin D Related/Nuclear Receptor
  3. Glucocorticoid Receptor
  4. 2-O-trans-p-Coumaroylalphitolic acid

2-O-trans-p-Coumaroylalphitolic acid (Zj7) is a triterpene which can be extracted from jujube plants. 2-O-trans-P-Coumaroyl alphitolic acid is a selective modulator of glucocorticoid receptor (GR). 2-O-trans-P-coumaroyl alphitolic acid can be used in the study of obesity.

For research use only. We do not sell to patients.

2-O-trans-p-Coumaroylalphitolic acid Chemical Structure

2-O-trans-p-Coumaroylalphitolic acid Chemical Structure

CAS No. : 67911-63-1

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2-O-trans-p-Coumaroylalphitolic acid Related Antibodies

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Description

2-O-trans-p-Coumaroylalphitolic acid (Zj7) is a triterpene which can be extracted from jujube plants. 2-O-trans-P-Coumaroyl alphitolic acid is a selective modulator of glucocorticoid receptor (GR). 2-O-trans-P-coumaroyl alphitolic acid can be used in the study of obesity[1].

In Vivo

2-O-trans-P-Coumaroylalphitolic acid (50 mg/kg, intrabitoneal injection every day for 2 weeks) has anti-obesity effects on obese mice with high fat diet (DIO) and db/db mice [1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: DIO mice[1]
Dosage: 50 mg/kg
Administration: i.p. every day for 2 weeks
Result: Enhanced insulin sensitivity.
Repressed. the expression of Agrp, Npy and Cdkn1a in the ARC
Molecular Weight

618.84

Formula

C39H54O6
CAS No.
SMILES

[H][C@]12CC[C@@]3([C@]4([C@@H](CC[C@@]4(CC[C@]3([C@@]1(CC[C@]5(C(C)([C@H]([C@@H](C[C@]25C)OC(/C=C/C6=CC=C(C=C6)O)=O)O)C)[H])C)C)C(O)=O)C(C)=C)[H])[H]
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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2-O-trans-p-Coumaroylalphitolic acid Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

2-O-trans-p-Coumaroylalphitolic acid67911-63-1Glucocorticoid ReceptorZj7glucocorticoid receptormodulatorDIOdb/db miceInhibitorinhibitorinhibit

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