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  6. 29-Nor-20-oxolupeol

29-Nor-20-oxolupeol, extracted from Impatiens basamina, reduces NO levels in LPS-activated murine microglial cells with an IC50 of 44.21 µM.

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29-Nor-20-oxolupeol Chemical Structure

29-Nor-20-oxolupeol Chemical Structure

CAS No. : 19891-85-1

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29-Nor-20-oxolupeol Related Antibodies

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Description

29-Nor-20-oxolupeol, extracted from Impatiens basamina, reduces NO levels in LPS-activated murine microglial cells with an IC50 of 44.21 µM[1].

Cellular Effect
Cell Line Type Value Description References
A2780 IC50
> 10 μM
Compound: 25
Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
Cytotoxicity against human A2780 cells after 96 hrs by MTT assay
[PMID: 24467317]
A549 IC50
> 10 μM
Compound: 25
Cytotoxicity against human A549 cells after 96 hrs by MTT assay
Cytotoxicity against human A549 cells after 96 hrs by MTT assay
[PMID: 24467317]
Bel-7402 IC50
> 10 μM
Compound: 25
Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay
Cytotoxicity against human Bel7402 cells after 96 hrs by MTT assay
[PMID: 24467317]
BGC-823 IC50
> 10 μM
Compound: 25
Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay
Cytotoxicity against human BGC823 cells after 96 hrs by MTT assay
[PMID: 24467317]
BV-2 IC50
6.09 μM
Compound: 25
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess method
[PMID: 24467317]
HCT-8 IC50
> 10 μM
Compound: 25
Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
Cytotoxicity against human HCT8 cells after 96 hrs by MTT assay
[PMID: 24467317]
Molecular Weight

428.69

Formula

C29H48O2
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

C[C@@]([C@@]1(CC[C@@]2([H])C3(C)C)C)(CC4)[C@@](CC[C@]1([H])[C@]2(CC[C@@H]3O)C)([H])[C@]([C@@H]5C(C)=O)([H])[C@@]4(CC5)C
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Purity & Documentation
References
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29-Nor-20-oxolupeol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

29-Nor-20-oxolupeol19891-85-1OthersLPSmurineNOproductionmicroglialcellsneuroprotectiveInhibitorinhibitorinhibit

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