2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. Porphobilinogen

Porphobilinogen could act as a phototoxin, a neurotoxin, and a metabotoxin.

For research use only. We do not sell to patients.

Porphobilinogen Chemical Structure

Porphobilinogen Chemical Structure

CAS No. : 487-90-1

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Based on 1 publication(s) in Google Scholar

Other Forms of Porphobilinogen:

Porphobilinogen Related Antibodies

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Description

Porphobilinogen could act as a phototoxin, a neurotoxin, and a metabotoxin.

IC50 & Target

Human Endogenous Metabolite

 

In Vitro

Porphobilinogen can act as a phototoxin, a neurotoxin, and a metabotoxin. A phototoxin leads to cell damage upon exposure to light. A neurotoxin causes damage to nerve cells and nerve tissues. A metabotoxin is an endogenously produced metabolite that causes adverse health effects at chronically high levels[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Porphobilinogen Related Antibodies
Clinical Trial
Molecular Weight

226.23

Formula

C10H14N2O4
CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

O=C(O)CCC1=CNC(CN)=C1CC(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

NH4OH : ≥ 10 mg/mL (44.20 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.4203 mL 22.1014 mL 44.2028 mL
5 mM 0.8841 mL 4.4203 mL 8.8406 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.00%

COA (309 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
NH4OH 1 mM 4.4203 mL 22.1014 mL 44.2028 mL 110.5070 mL
5 mM 0.8841 mL 4.4203 mL 8.8406 mL 22.1014 mL
10 mM 0.4420 mL 2.2101 mL 4.4203 mL 11.0507 mL
15 mM 0.2947 mL 1.4734 mL 2.9469 mL 7.3671 mL
20 mM 0.2210 mL 1.1051 mL 2.2101 mL 5.5254 mL
25 mM 0.1768 mL 0.8841 mL 1.7681 mL 4.4203 mL
30 mM 0.1473 mL 0.7367 mL 1.4734 mL 3.6836 mL
40 mM 0.1105 mL 0.5525 mL 1.1051 mL 2.7627 mL
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Porphobilinogen Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Porphobilinogen487-90-1Endogenous MetaboliteInhibitorinhibitorinhibit

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