2. Metabolic Enzyme/Protease
  3. 17β-HSD
  4. 3-Acetyl-7-Hydroxycoumarin

3-Acetyl-7-Hydroxycoumarin (Compound 2) is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17β-HSD1 at 6 μM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis.

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3-Acetyl-7-Hydroxycoumarin Chemical Structure

3-Acetyl-7-Hydroxycoumarin Chemical Structure

CAS No. : 10441-27-7

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Description

3-Acetyl-7-Hydroxycoumarin (Compound 2) is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17β-HSD1 at 6 μM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis[1].

Molecular Weight

204.18

Formula

C11H8O4
CAS No.
SMILES

CC(=O)C1=CC2=C(C=C(C=C2)O)OC1=O
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Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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3-Acetyl-7-Hydroxycoumarin Related Classifications

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Keywords:

3-Acetyl-7-Hydroxycoumarin10441-27-717β-HSD17beta-HSD17β-hydroxysteroid dehydrogenases17 beta-hydroxysteroid dehydrogenase17-beta-hydroxysteroid dehydrogenase type 1breast cancer and endometriosisInhibitorinhibitorinhibit

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