2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. 3-AQC

3-AQC, a piperazinylquinoxaline derivative, is a potent and competitive 5-HT3 receptor antagonist.

For research use only. We do not sell to patients.

3-AQC Chemical Structure

3-AQC Chemical Structure

CAS No. : 201216-42-4

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Based on 1 publication(s) in Google Scholar

3-AQC Related Antibodies

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5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

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Description

3-AQC, a piperazinylquinoxaline derivative, is a potent and competitive 5-HT3 receptor antagonist[1].

IC50 & Target[1]

5-HT3 Receptor

 

In Vitro

3-AQC (compound 7e) is almost 2 orders of magnitude more potent than Tropisetron (HY-B0072). The pA2 of antagonism to 2-methyl-5HT in guinea pig ileum is 10.2[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

3-AQC Related Antibodies
Molecular Weight

395.41

Formula

C20H21N5O4
CAS No.
SMILES

N#CC1=NC2=CC=CC=C2N=C1N3CCN(CC=C)CC3.OC(/C=C\C(O)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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3-AQC Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-AQC201216-42-45-HT ReceptorSerotonin Receptor5-hydroxytryptamine ReceptorInhibitorinhibitorinhibit

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HY-101062
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