2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 3-Hydroxybutyric acid-d4 sodium

3-Hydroxybutyric acid-d4 sodium  (Synonyms: β-Hydroxybutyric acid-d4 (sodium))

Cat. No.: HY-113378S Purity: 99.72%
SDS COA Handling Instructions

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3-Hydroxybutyric acid-d4 (sodium) is the deuterium labeled 3-Hydroxybutyric acid. 3-Hydroxybutyric acid (β-Hydroxybutyric acid) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid can modulate the properties of membrane lipids[1].

For research use only. We do not sell to patients.

3-Hydroxybutyric acid-d<sub>4</sub> sodium Chemical Structure

3-Hydroxybutyric acid-d4 sodium Chemical Structure

CAS No. : 1219804-68-8

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1 mg USD 40 In-stock
5 mg USD 140 In-stock
10 mg USD 250 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 3-Hydroxybutyric acid-d4 sodium:

3-Hydroxybutyric acid-d4 sodium Related Antibodies

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  • Purity & Documentation

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Description

3-Hydroxybutyric acid-d4 (sodium) is the deuterium labeled 3-Hydroxybutyric acid. 3-Hydroxybutyric acid (β-Hydroxybutyric acid) is a metabolite that is elevated in type I diabetes. 3-Hydroxybutyric acid can modulate the properties of membrane lipids[1].

Cellular Effect
Cell Line Type Value Description References
HEK293 IC50
> 15 mM
Compound: 10
Cytotoxicity against HEK293 cells harboring pendrin P123S mutant after 72 hrs by MTT assay
Cytotoxicity against HEK293 cells harboring pendrin P123S mutant after 72 hrs by MTT assay
[PMID: 28341401]
In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

3-Hydroxybutyric acid-d4 sodium Related Antibodies
Molecular Weight

130.11

Formula

C4H3D4NaO3
CAS No.
Unlabeled CAS

150-83-4
Appearance

Solid

Color

White to off-white

SMILES

[2H]C([2H])([2H])C([2H])(O)CC(O[Na])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (768.58 mM)

PBS (pH 7.2) : ≥ 10 mg/mL (76.86 mM)

Ethanol : ≥ 5 mg/mL (38.43 mM)

Ethanol : ≥ 5 mg/mL (38.43 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.6858 mL 38.4290 mL 76.8580 mL
5 mM 1.5372 mL 7.6858 mL 15.3716 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: 99.72%

SDS (252 KB)

COA (250 KB) HNMR (670 KB) RP-HPLC (875 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
Ethanol / Ethanol / PBS (pH 7.2) / H2O 1 mM 7.6858 mL 38.4290 mL 76.8580 mL 192.1451 mL
5 mM 1.5372 mL 7.6858 mL 15.3716 mL 38.4290 mL
10 mM 0.7686 mL 3.8429 mL 7.6858 mL 19.2145 mL
15 mM 0.5124 mL 2.5619 mL 5.1239 mL 12.8097 mL
20 mM 0.3843 mL 1.9215 mL 3.8429 mL 9.6073 mL
25 mM 0.3074 mL 1.5372 mL 3.0743 mL 7.6858 mL
30 mM 0.2562 mL 1.2810 mL 2.5619 mL 6.4048 mL
PBS (pH 7.2) / H2O 40 mM 0.1921 mL 0.9607 mL 1.9215 mL 4.8036 mL
50 mM 0.1537 mL 0.7686 mL 1.5372 mL 3.8429 mL
60 mM 0.1281 mL 0.6405 mL 1.2810 mL 3.2024 mL
H2O 80 mM 0.0961 mL 0.4804 mL 0.9607 mL 2.4018 mL
100 mM 0.0769 mL 0.3843 mL 0.7686 mL 1.9215 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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3-Hydroxybutyric acid-d4 sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Hydroxybutyric acid-d41219804-68-8β-Hydroxybutyric acid-d4Endogenous MetaboliteInhibitorinhibitorinhibit

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