2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite
  4. 3-Nitro-L-tyrosine-d3

3-Nitro-L-tyrosine-d3 is the deuterium labeled 3-Nitro-L-tyrosine. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions[1][2].

For research use only. We do not sell to patients.

3-Nitro-L-tyrosine-d<sub>3</sub> Chemical Structure

3-Nitro-L-tyrosine-d3 Chemical Structure

CAS No. : 213386-10-8

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5 mg USD 480 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 3-Nitro-L-tyrosine-d3:

3-Nitro-L-tyrosine-d3 Related Antibodies

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Description

3-Nitro-L-tyrosine-d3 is the deuterium labeled 3-Nitro-L-tyrosine. 3-Nitro-L-tyrosine is a biomarker of nitrogen free radical species modified proteins in systemic autoimmunogenic conditions[1][2].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

3-Nitro-L-tyrosine-d3 Related Antibodies
Molecular Weight

229.20

Formula

C9H7D3N2O5
CAS No.
Unlabeled CAS

621-44-3
Appearance

Solid

Color

Off-white to light yellow

SMILES

N[C@@H](CC1=C([2H])C([N+]([O-])=O)=C(O)C([2H])=C1[2H])C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 5 mg/mL (21.82 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)

H2O : 5 mg/mL (21.82 mM; ultrasonic and warming and adjust pH to 2 with HCl and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.3630 mL 21.8150 mL 43.6300 mL
5 mM 0.8726 mL 4.3630 mL 8.7260 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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In Vivo Dissolution Calculator
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Purity & Documentation

Purity: ≥99.0%

COA (249 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O / H2O 1 mM 4.3630 mL 21.8150 mL 43.6300 mL 109.0750 mL
5 mM 0.8726 mL 4.3630 mL 8.7260 mL 21.8150 mL
10 mM 0.4363 mL 2.1815 mL 4.3630 mL 10.9075 mL
15 mM 0.2909 mL 1.4543 mL 2.9087 mL 7.2717 mL
20 mM 0.2182 mL 1.0908 mL 2.1815 mL 5.4538 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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3-Nitro-L-tyrosine-d3 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-Nitro-L-tyrosine-d3213386-10-8Endogenous MetaboliteInhibitorinhibitorinhibit

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