2. Metabolic Enzyme/Protease Neuronal Signaling
  3. COMT
  4. 3-O-Methyltolcapone-d7

3-O-Methyltolcapone-d7  (Synonyms: Ro 40-7591 d7)

Cat. No.: HY-100642S Purity: ≥99.0%
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3-O-Methyltolcapone-d7 is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease[1][2].

For research use only. We do not sell to patients.

3-O-Methyltolcapone-d<sub>7</sub> Chemical Structure

3-O-Methyltolcapone-d7 Chemical Structure

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1 mg USD 490 In-stock
5 mg USD 1470 In-stock
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Based on 1 publication(s) in Google Scholar

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3-O-Methyltolcapone-d7 Related Antibodies

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Description

3-O-Methyltolcapone-d7 is a deuterium labeled 3-O-Methyltolcapone. 3-O-Methyltolcapone is a metabolite of Tolcapone. Tolcapone is an orally active, reversible, selective and potent COMT inhibitor. Tolcapone crosses the blood-brain barrier, and can be used for treatment of Parkinson's disease[1][2].

IC50 & Target

COMT[1][2]
Molecular Weight

294.31

Formula

C15H6D7NO5
Unlabeled CAS

134612-80-9
Appearance

Solid

Color

Light yellow to yellow

SMILES

OC(C(OC)=C1)=C(C=C1C(C2=C([2H])C([2H])=C(C([2H])=C2[2H])C([2H])([2H])[2H])=O)[N+]([O-])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation
References
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3-O-Methyltolcapone-d7 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3-O-Methyltolcapone-d7Ro 40-7591 d7COMTCatechol-O-methyltransferaseMetabolitedeuteriumlabeledTolcaponeblood-brainbarrierParkinson'sdiseaseInhibitorinhibitorinhibit

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