1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. 3α-Hydroxysteroid Dehydrogenase, Microorganism

3α-Hydroxysteroid Dehydrogenase, Microorganism  (Synonyms: 3α-HSD)

Cat. No.: HY-P2901 Purity: 90.00%
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3α-Hydroxysteroid Dehydrogenase, Microorganism (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism.

For research use only. We do not sell to patients.

3α-Hydroxysteroid Dehydrogenase, Microorganism Chemical Structure

3α-Hydroxysteroid Dehydrogenase, Microorganism Chemical Structure

CAS No. : 9028-56-2

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500U USD 65 In-stock
1KU USD 105 In-stock

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This product is a controlled substance and not for sale in your territory.

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Description

3α-Hydroxysteroid Dehydrogenase, Microorganism (3α-HSD) is an enzyme encoded by the AKR1C4 gene, which can catalyze the conversion of 3-ketosteroids into 3α-hydroxy compounds. 3α-Hydroxysteroid dehydrogenase plays an important role in the inactivation of androgen DHT, and can convert DHT into 3α-androstanediol with weak androgen activity, which can be used in the research of hirsutism[1].

In Vitro

Product Information
This product is a genetically recombinant product and has no animal origin. 3α-Hydroxysteroid dehydrogenase is used clinically to catalyze the dehydrogenation reaction of hydroxysteroids and is used for the clinical detection of total bile acid.

Molecular weight: about 28 kDa (SDS-PAGE detection)
Isoelectric point: 4.8
Optimum pH: 7.0-9.0
Inhibitors: Hg2+, Ag+, etc.
Instructions
Dissolved in ddH2O at concentrations below 50 mg/mL to avoid repeated freezing and thawing. Or dissolve in buffer according to specific experimental references.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

[3a-Hydroxysteroid Dehydrogenase, Microorganism]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

H2O : 50 mg/mL (Need ultrasonic)

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This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
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Purity & Documentation

Purity: 90.00%

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3α-Hydroxysteroid Dehydrogenase, Microorganism Related Classifications

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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3α-Hydroxysteroid Dehydrogenase, Microorganism
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