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  5. 3β-Methoxy-2,3-dihydrowithaferin A

3β-Methoxy-2,3-dihydrowithaferin A  (Synonyms: Quresimin A)

Cat. No.: HY-N5131
Handling Instructions Technical Support

3β-Methoxy-2,3-dihydrowithaferin A is one of withanolides found in Withania somnifera.

For research use only. We do not sell to patients.

3β-Methoxy-2,3-dihydrowithaferin A Chemical Structure

3β-Methoxy-2,3-dihydrowithaferin A Chemical Structure

CAS No. : 73365-94-3

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Based on 1 publication(s) in Google Scholar

3β-Methoxy-2,3-dihydrowithaferin A Related Antibodies

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Description

3β-Methoxy-2,3-dihydrowithaferin A is one of withanolides found in Withania somnifera[1].

Cellular Effect
Cell Line Type Value Description References
A549 IC50
> 40 μM
Compound: 44
Cytotoxicity against human A549 cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
A549 IC50
> 40 μM
Compound: 44
Cytotoxicity against human A549 cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
B16-F10 IC50
> 10 μM
Compound: 17
Cytotoxicity against mouse B16F10 cells after 72 hrs by MTS assay
Cytotoxicity against mouse B16F10 cells after 72 hrs by MTS assay
[PMID: 22098611]
C3H 10T1/2 IC50
> 25 μM
Compound: 5
Cytotoxicity against mouse C3H10T1/2 cells after 24 hrs by FMCA
Cytotoxicity against mouse C3H10T1/2 cells after 24 hrs by FMCA
[PMID: 26169123]
DU-145 IC50
> 25 μM
Compound: 5
Cytotoxicity against human DU145 cells after 24 hrs by FMCA
Cytotoxicity against human DU145 cells after 24 hrs by FMCA
[PMID: 26169123]
HaCaT IC50
> 25 μM
Compound: 5
Inhibition of hedgehog/GLI1-mediated transcriptional activity in human HaCaT cells after 12 hrs by luciferase assay
Inhibition of hedgehog/GLI1-mediated transcriptional activity in human HaCaT cells after 12 hrs by luciferase assay
[PMID: 26169123]
HeLa IC50
> 40 μM
Compound: 44
Cytotoxicity against human HeLa cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
HeLa IC50
> 40 μM
Compound: 44
Cytotoxicity against human HeLa cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
MCF7 IC50
> 25 μM
Compound: 5
Cytotoxicity against human MCF7 cells after 24 hrs by FMCA
Cytotoxicity against human MCF7 cells after 24 hrs by FMCA
[PMID: 26169123]
MCF7 IC50
> 40 μM
Compound: 44
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
MCF7 IC50
> 40 μM
Compound: 44
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against human MCF7 cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
PANC-1 IC50
> 25 μM
Compound: 5
Cytotoxicity against human PANC1 cells after 24 hrs by FMCA
Cytotoxicity against human PANC1 cells after 24 hrs by FMCA
[PMID: 26169123]
SK-MEL-28 IC50
> 10 μM
Compound: 17
Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTS assay
Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTS assay
[PMID: 22098611]
Vero IC50
> 40 μM
Compound: 44
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability using compound addition to cell culture cells in lag phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
Vero IC50
> 40 μM
Compound: 44
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability using compound addition to cell culture cells in log phase of growth and incubated for 48 hrs by MTT assay
[PMID: 28923386]
Molecular Weight

502.64

Formula

C29H42O7
CAS No.
SMILES

C[C@]12[C@@]3([C@H]([C@H](CC2=O)OC)O)[C@](C[C@]4([H])[C@]1([H])CC[C@]5([C@@]4([H])CC[C@]5([H])[C@@H]([C@@]6([H])CC(C)=C(C(O6)=O)CO)C)C)([H])O3
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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3β-Methoxy-2,3-dihydrowithaferin A Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

3β-Methoxy-2,3-dihydrowithaferin A73365-94-3Quresimin AOthersInhibitorinhibitorinhibit

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3β-Methoxy-2,3-dihydrowithaferin A
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