4,5'-Dimethylangelicin-NHS

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4,5'-Dimethylangelicin-NHS is a modified 4,5'-Dimethylangelicin containing an NHS. 4,5'-Dimethylangelicin is an angular furocoumarin with photochemical and photosensitizing properties. 4,5'-Dimethylangelicin can inhibit the DNA and RNA syntheses in Ehrlich ascites tumor cells alter irradiation at 365 nm. 4,5'-Dimethylangelicin has potential as a photochemotherapy agent.

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4,5'-Dimethylangelicin-NHS Chemical Structure

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Description	4,5'-Dimethylangelicin-NHS is a modified 4,5'-Dimethylangelicin containing an NHS. 4,5'-Dimethylangelicin is an angular furocoumarin with photochemical and photosensitizing properties. 4,5'-Dimethylangelicin can inhibit the DNA and RNA syntheses in Ehrlich ascites tumor cells alter irradiation at 365 nm. 4,5'-Dimethylangelicin has potential as a photochemotherapy agent^[1]^[2].
IC₅₀ & Target	DNA/RNA synthesis^[2]
Molecular Weight	429.44
Formula	C₂₁H₁₉NO₇S
SMILES	CC1=CC(OC2=C1C=CC3=C2C(CSCCC(ON4C(CCC4=O)=O)=O)=C(C)O3)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (273 KB) Handling Instructions (2659 KB)
References	[1]. Bordin F, et al. 4,5'-dimethylangelicin: a new DNA-photobinding monofunctional agent. Photochem Photobiol. 1979 Jun;29(6):1063-70. [Content Brief] [2]. Guiotto A, et al. A new water soluble derivative of 4,5'-dimethylangelicin as a potential agent for photochemotherapy. Farmaco Sci. 1981 Jul;36(7):536-50. [Content Brief]