1. Anti-infection
  2. Parasite
  3. 4-(Bromomethyl)benzoic acid

4-(Bromomethyl)benzoic acid  (Synonyms: 4-Carboxybenzyl bromide)

Cat. No.: HY-21496
Data Sheet Handling Instructions Technical Support

4-(Bromomethyl)benzoic acid (4-Carboxybenzyl bromide) is an antiparasitic agent with low activity against Leishmania amazonensis and Trypanosoma cruzi. 4-(Bromomethyl)benzoic acid has certain cytotoxicity to PBMCs, with an IC50 of 88.8 μM.

For research use only. We do not sell to patients.

4-(Bromomethyl)benzoic acid Chemical Structure

4-(Bromomethyl)benzoic acid Chemical Structure

CAS No. : 6232-88-8

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10 g USD 38 In-stock
25 g USD 66 In-stock
50 g USD 99 In-stock
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Description

4-(Bromomethyl)benzoic acid (4-Carboxybenzyl bromide) is an antiparasitic agent with low activity against Leishmania amazonensis and Trypanosoma cruzi. 4-(Bromomethyl)benzoic acid has certain cytotoxicity to PBMCs, with an IC50 of 88.8 μM[1].

Molecular Weight

215.04

Formula

C8H7BrO2

CAS No.
Appearance

Solid

SMILES

BrCC1=CC=C(C(O)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (139.51 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.6503 mL 23.2515 mL 46.5030 mL
5 mM 0.9301 mL 4.6503 mL 9.3006 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 4.6503 mL 23.2515 mL 46.5030 mL 116.2574 mL
5 mM 0.9301 mL 4.6503 mL 9.3006 mL 23.2515 mL
10 mM 0.4650 mL 2.3251 mL 4.6503 mL 11.6257 mL
15 mM 0.3100 mL 1.5501 mL 3.1002 mL 7.7505 mL
20 mM 0.2325 mL 1.1626 mL 2.3251 mL 5.8129 mL
25 mM 0.1860 mL 0.9301 mL 1.8601 mL 4.6503 mL
30 mM 0.1550 mL 0.7750 mL 1.5501 mL 3.8752 mL
40 mM 0.1163 mL 0.5813 mL 1.1626 mL 2.9064 mL
50 mM 0.0930 mL 0.4650 mL 0.9301 mL 2.3251 mL
60 mM 0.0775 mL 0.3875 mL 0.7750 mL 1.9376 mL
80 mM 0.0581 mL 0.2906 mL 0.5813 mL 1.4532 mL
100 mM 0.0465 mL 0.2325 mL 0.4650 mL 1.1626 mL
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Product Name:
4-(Bromomethyl)benzoic acid
Cat. No.:
HY-21496
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