4-(Bromomethyl)benzoic acid (Synonyms: 4-Carboxybenzyl bromide)

Cat. No.: HY-21496: FAQs
Data Sheet Handling Instructions Technical Support

4-(Bromomethyl)benzoic acid (4-Carboxybenzyl bromide) is an antiparasitic agent with low activity against Leishmania amazonensis and Trypanosoma cruzi. 4-(Bromomethyl)benzoic acid has certain cytotoxicity to PBMCs, with an IC₅₀ of 88.8 μM.

For research use only. We do not sell to patients.

4-(Bromomethyl)benzoic acid Chemical Structure

CAS No. : 6232-88-8

Size	Stock	Quantity
5 g	In-stock	Estimated Time of Arrival: December 31
10 g	In-stock	Estimated Time of Arrival: December 31
25 g	In-stock	Estimated Time of Arrival: December 31
50 g	In-stock	Estimated Time of Arrival: December 31
100 g	In-stock	Estimated Time of Arrival: December 31
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Description

Molecular Weight

215.04

Formula

C₈H₇BrO₂

CAS No.

6232-88-8

Appearance

Solid

SMILES

BrCC1=CC=C(C(O)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : ≥ 30 mg/mL (139.51 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.6503 mL	23.2515 mL	46.5030 mL
5 mM	0.9301 mL	4.6503 mL	9.3006 mL
10 mM	0.4650 mL	2.3251 mL	4.6503 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Lopes MS, et al. Synthesis and evaluation of the anti parasitic activity of aromatic nitro compounds. Eur J Med Chem. 2011 Nov;46(11):5443-7. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.6503 mL	23.2515 mL	46.5030 mL	116.2574 mL
	5 mM	0.9301 mL	4.6503 mL	9.3006 mL	23.2515 mL
	10 mM	0.4650 mL	2.3251 mL	4.6503 mL	11.6257 mL
	15 mM	0.3100 mL	1.5501 mL	3.1002 mL	7.7505 mL
	20 mM	0.2325 mL	1.1626 mL	2.3251 mL	5.8129 mL
	25 mM	0.1860 mL	0.9301 mL	1.8601 mL	4.6503 mL
	30 mM	0.1550 mL	0.7750 mL	1.5501 mL	3.8752 mL
	40 mM	0.1163 mL	0.5813 mL	1.1626 mL	2.9064 mL
	50 mM	0.0930 mL	0.4650 mL	0.9301 mL	2.3251 mL
	60 mM	0.0775 mL	0.3875 mL	0.7750 mL	1.9376 mL
	80 mM	0.0581 mL	0.2906 mL	0.5813 mL	1.4532 mL
	100 mM	0.0465 mL	0.2325 mL	0.4650 mL	1.1626 mL

4-(Bromomethyl)benzoic acid Related Classifications

Infection

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-(Bromomethyl)benzoic acid6232-88-84-CarboxybenzylParasitePBMCsLeishmania (L.) amazonensisTrypanosoma cruziInhibitorinhibitorinhibit

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4-(Bromomethyl)benzoic acid (Synonyms: 4-Carboxybenzyl bromide)

4-(Bromomethyl)benzoic acid Related Antibodies

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