2. Cell Cycle/DNA Damage
  3. Nucleoside Antimetabolite/Analog
  4. 4'-C-Azidouridine

4'-C-azidouridine (4'-Azidouridine) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents. 4'-C-Azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

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4'-C-Azidouridine Chemical Structure

4'-C-Azidouridine Chemical Structure

CAS No. : 139442-01-6

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4'-C-Azidouridine Related Antibodies

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Description

4'-C-azidouridine (4'-Azidouridine) is a uridine analogue. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1]. 4'-C-Azidouridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Molecular Weight

285.21

Formula

C9H11N5O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O[C@@H]1[C@H](O)[C@](CO)(N=[N+]=[N-])O[C@H]1N2C(NC(C=C2)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (350.62 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5062 mL 17.5309 mL 35.0619 mL
5 mM 0.7012 mL 3.5062 mL 7.0124 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

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In Vivo Dissolution Calculator
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Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5062 mL 17.5309 mL 35.0619 mL 87.6547 mL
5 mM 0.7012 mL 3.5062 mL 7.0124 mL 17.5309 mL
10 mM 0.3506 mL 1.7531 mL 3.5062 mL 8.7655 mL
15 mM 0.2337 mL 1.1687 mL 2.3375 mL 5.8436 mL
20 mM 0.1753 mL 0.8765 mL 1.7531 mL 4.3827 mL
25 mM 0.1402 mL 0.7012 mL 1.4025 mL 3.5062 mL
30 mM 0.1169 mL 0.5844 mL 1.1687 mL 2.9218 mL
40 mM 0.0877 mL 0.4383 mL 0.8765 mL 2.1914 mL
50 mM 0.0701 mL 0.3506 mL 0.7012 mL 1.7531 mL
60 mM 0.0584 mL 0.2922 mL 0.5844 mL 1.4609 mL
80 mM 0.0438 mL 0.2191 mL 0.4383 mL 1.0957 mL
100 mM 0.0351 mL 0.1753 mL 0.3506 mL 0.8765 mL
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4'-C-Azidouridine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4'-C-Azidouridine139442-01-64'-AzidouridineNucleoside Antimetabolite/AnaloganticonvulsantanxiolyticantiepilepticantihypertensiveInhibitorinhibitorinhibit

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