2. Autophagy PI3K/Akt/mTOR
  3. Autophagy mTOR
  4. 4-FPBUA

4-FPBUA is a semisynthetic analog of usnic acid (HY-W015883) that can enhance cellular blood-brain barrier (BBB) function and increase the transport of Amyloid β (Aβ) across monolayer cells. 4-FPBUA is also an inhibitor of mTOR, capable of enhancing cellular Autophagy, thereby reversing BBB disruption in vivo and being utilized in research for Alzheimer's disease.

For research use only. We do not sell to patients.

4-FPBUA Chemical Structure

4-FPBUA Chemical Structure

CAS No. : 2089636-93-9

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4-FPBUA Related Antibodies

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Description

4-FPBUA is a semisynthetic analog of usnic acid (HY-W015883) that can enhance cellular blood-brain barrier (BBB) function and increase the transport of Amyloid β (Aβ) across monolayer cells. 4-FPBUA is also an inhibitor of mTOR, capable of enhancing cellular Autophagy, thereby reversing BBB disruption in vivo and being utilized in research for Alzheimer's disease[1].

Molecular Weight

526.51

Formula

C31H23FO7
CAS No.
SMILES

C[C@]12C3=C(O)C(C)=C(O)C(C(/C=C/C4=CC=C(C5=CC=C(C=C5)F)C=C4)=O)=C3OC1=CC(O)=C(C2=O)C(C)=O
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Room temperature in continental US; may vary elsewhere.
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References
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4-FPBUA Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-FPBUA2089636-93-9AutophagymTORMammalian target of RapamycinAlzheimer’s disease (AD)blood–brain barrier (BBB)bEnd3usnic acidInhibitorinhibitorinhibit

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