2. Immunology/Inflammation NF-κB
  3. Complement System Toll-like Receptor (TLR) NF-κB
  4. 4-Octylphenol

4-Octylphenol is a hormone disruptor that has gender-specific effects on male reproductive cells, significantly reducing the mitotic index and the number of spermatogonia. 4-Octylphenol can cause inflammatory damage to fish gills by activating the complement system through the C3a/C3aR axis and the C5a/C5aR1 axis, this leads to complement activation and causes immune suppression due to the imbalance between Th1/Th2 cells and regulatory T cells (Treg)/Th17 cells, as well as inflammatory damage via the Toll-like receptor 7 (Toll-like Receptor (TLR))/IκBα/NF-κB pathway.

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4-Octylphenol Chemical Structure

4-Octylphenol Chemical Structure

CAS No. : 1806-26-4

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Other Forms of 4-Octylphenol:

4-Octylphenol Related Antibodies

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Description

4-Octylphenol is a hormone disruptor that has gender-specific effects on male reproductive cells, significantly reducing the mitotic index and the number of spermatogonia. 4-Octylphenol can cause inflammatory damage to fish gills by activating the complement system through the C3a/C3aR axis and the C5a/C5aR1 axis, this leads to complement activation and causes immune suppression due to the imbalance between Th1/Th2 cells and regulatory T cells (Treg)/Th17 cells, as well as inflammatory damage via the Toll-like receptor 7 (Toll-like Receptor (TLR))/IκBα/NF-κB pathway[1][2].

Molecular Weight

206.32

Formula

C14H22O
CAS No.
Appearance

Solid

Color

Off-white to light brown

SMILES

CCCCCCCCC1=CC=C(C=C1)O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

Purity & Documentation
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4-Octylphenol Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Octylphenol1806-26-4Complement SystemToll-like Receptor (TLR)NF-κBNuclear factor-κBNuclear factor-kappaBHormonesmitosismale germ cellsregulatory T cellsInhibitorinhibitorinhibit

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