2. Antibody-drug Conjugate/ADC Related
  3. ADC Linker
  4. 4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene 

Cat. No.: HY-133538
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4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

For research use only. We do not sell to patients.

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene Chemical Structure

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene Chemical Structure

CAS No. : 160854-54-6

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4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene Related Antibodies

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Description

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC50 & Target

Disulfide Cleavable Linker

 

Non-cleavable Linker

 

In Vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene Related Antibodies
Molecular Weight

374.43

Formula

C17H14N2O4S2
CAS No.
SMILES

O=C(ON1C(CCC1=O)=O)C2=CC=C(CSSC3=NC=CC=C3)C=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene Related Classifications

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  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene160854-54-6ADC LinkerAntibody-drug conjugates linkerInhibitorinhibitorinhibit

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4-Succinimidyl-oxycarbonyl-α-(2-pyridyldithio)toluene
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