4'-Trifluoromethyl-2-biphenyl carboxylic acid is an orally active hypolipidemic agent.

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4'-Trifluoromethyl-2-biphenyl carboxylic acid Chemical Structure

Chemical Structure

CAS No. : 84392-17-6

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Description

4'-Trifluoromethyl-2-biphenyl carboxylic acid is an orally active hypolipidemic agent[1]. In Vivo:4'-Trifluoromethyl-2-biphenyl carboxylic acid (15-60 mg/kg, p.o., twice a day) shows hypolipidemic activity in diet-induced hypercholesterolemic African green monkeys[1].

In Vivo
Animal Model: Diet-induced hypercholesterolemic African green monkeys[5]
Dosage: 15-60 mg/kg
Administration: Oral administration (p.o.)
Result: Reduced serum LDL-cholesterol concentrations.
Molecular Weight

266.22

Formula

C14H9F3O2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C1=CC=CC=C1C2=CC=C(C(F)(F)F)C=C2)O

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Room temperature in continental US; may vary elsewhere.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
4'-Trifluoromethyl-2-biphenyl carboxylic acid
Cat. No.:
HY-34781
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