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  2. Mitochondrial Metabolism Reactive Oxygen Species
  3. 5-Acetamide-Butenolide

5-Acetamide-Butenolide  (Synonyms: Butenolide)

Cat. No.: HY-W402074
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5-Acetamide-Butenolide (butenolide) is a mycotoxin with pro-oxidant activity, which is found in Fusarium. 5-Acetamide-Butenolide disrupts the mitochondrial membrane potential in primary neonatal rat cardiomyocytes. 5-Acetamide-Butenolide also induces the production of thiobarbituric acid reactive substances (TBARS) in isolated rat myocardial mitochondria. 5-Acetamide-Butenolide increases the production of reactive oxygen species (ROS), decreases the levels of GSH and reduces the viability of HepG2 cells.

For research use only. We do not sell to patients.

5-Acetamide-Butenolide Chemical Structure

5-Acetamide-Butenolide Chemical Structure

CAS No. : 16275-44-8

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Description

5-Acetamide-Butenolide (butenolide) is a mycotoxin with pro-oxidant activity, which is found in Fusarium. 5-Acetamide-Butenolide disrupts the mitochondrial membrane potential in primary neonatal rat cardiomyocytes. 5-Acetamide-Butenolide also induces the production of thiobarbituric acid reactive substances (TBARS) in isolated rat myocardial mitochondria. 5-Acetamide-Butenolide increases the production of reactive oxygen species (ROS), decreases the levels of GSH and reduces the viability of HepG2 cells[1][2][3].

Molecular Weight

141.12

Formula

C6H7NO3

CAS No.
SMILES

O=C1OC(NC(C)=O)C=C1

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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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5-Acetamide-Butenolide
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