5-Bromopentanoyl chloride

Cat. No.: HY-43538 Purity: 98.63%: FAQs
Data Sheet SDS COA Handling Instructions

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5-Bromopentanoyl chloride is a PROTAC linker in PROTAC ATR degrader-2 (HY-161615), and can be used for synthesis of PROTACs.

For research use only. We do not sell to patients.

5-Bromopentanoyl chloride Chemical Structure

CAS No. : 4509-90-4

Size	Price	Stock	Quantity
5 g	USD 25	In-stock	Estimated Time of Arrival: December 31
10 g	USD 41	In-stock	Estimated Time of Arrival: December 31
50 g		Get quote

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Description	5-Bromopentanoyl chloride is a PROTAC linker in PROTAC ATR degrader-2 (HY-161615), and can be used for synthesis of PROTACs^[1].
Molecular Weight	199.47
Formula	C₅H₈BrClO
CAS No.	4509-90-4
Appearance	Liquid
Color	Colorless to light yellow
SMILES	O=C(Cl)CCCCBr
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	-20°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation	Purity: 98.63% Select Batch: Data Sheet (262 KB) SDS (476 KB) COA (242 KB) HNMR (223 KB) MS (70 KB) GC (254 KB) Handling Instructions (2659 KB)
References	[1]. Wang Y, et al. Discovery of Selective and Potent ATR Degrader for Exploration its Kinase-Independent Functions in Acute Myeloid Leukemia Cells. Angew Chem Int Ed Engl. 2024 Apr 22;63(17):e202318568. [Content Brief]

5-Bromopentanoyl chloride Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass		Concentration		Volume		Molecular Weight *
	=		×		×

The dilution calculator equation

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)	×	Volume _(start)	=	Concentration _(final)	×	Volume _(final)
	×		=		×
C1		V1		C2		V2

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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5-Bromopentanoyl4509-90-4PROTAC LinkersInhibitorinhibitorinhibit

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5-Bromopentanoyl chloride

5-Bromopentanoyl chloride Related Antibodies

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