5-Cholesten-24(RS)-methyl-3β-ol-d₃

Name: 5-Cholesten-24(RS)-methyl-3β-ol-d 3
Brand: MedChemExpress
SKU: HY-146627S
Rating: 4.5 (1 reviews)

Cat. No.: HY-146627S Purity: 99.21%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

5-Cholesten-24(RS)-methyl-3β-ol-d₃ is the deuterium labeled 5-Cholesten-24(RS)-methyl-3β-ol[1].

For research use only. We do not sell to patients.

5-Cholesten-24(RS)-methyl-3β-ol-d<sub>3</sub> Chemical Structure

5-Cholesten-24(RS)-methyl-3β-ol-d₃ Chemical Structure

Size	Price	Stock	Quantity
1 mg	USD 250	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

5-Cholesten-24(RS)-methyl-3β-ol-d₃ is the deuterium labeled 5-Cholesten-24(RS)-methyl-3β-ol[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

403.70

Formula

C₂₈H₄₅D₃O

Appearance

Solid

Color

White to off-white

SMILES

C[C@@]12[C@](CC[C@]2([H])[C@H](C)CCC(C([2H])([2H])[2H])C(C)C)([H])[C@@]3([H])[C@@](CC1)([H])[C@@]4(C(C[C@H](CC4)O)=CC3)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

Ethanol : 10 mg/mL (24.77 mM; Need ultrasonic and warming)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.4771 mL	12.3854 mL	24.7709 mL
5 mM	0.4954 mL	2.4771 mL	4.9542 mL
10 mM	0.2477 mL	1.2385 mL	2.4771 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.21%

Select Batch:

Data Sheet (272 KB) SDS (252 KB)

COA (251 KB) HNMR (2943 KB) RP-HPLC (2993 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

Ethanol	1 mM	2.4771 mL	12.3854 mL	24.7709 mL	61.9272 mL
	5 mM	0.4954 mL	2.4771 mL	4.9542 mL	12.3854 mL
	10 mM	0.2477 mL	1.2385 mL	2.4771 mL	6.1927 mL
	15 mM	0.1651 mL	0.8257 mL	1.6514 mL	4.1285 mL
	20 mM	0.1239 mL	0.6193 mL	1.2385 mL	3.0964 mL